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Topoisomerase I (E. coli) catalyzes the relaxation of negatively supercoiled DNA. Topoisomerase I has also been implicated in knotting and unknotting DNA (1) and in linking complementary rings of single-stranded DNA into double-stranded rings (2). The intact holoenzyme is a 97 kDa protein. Product Source
An E. coli strain containing the cloned topA gene- This product is related to the following categories:
- DNA Repair Enzymes and Structure-specific Endonucleases Products
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